湖南师范大学：饮食成分、菌群代谢物与人体健康（综述）
- ①不同的膳食成分可被肠道菌群转化为不同的代谢产物，通过多种机制影响人体健康；
- ②碳水化合物中，低聚木糖、低聚果糖、抗性淀粉等可被转化为短链脂肪酸和有机酸等；
- ③色氨酸可被代谢为吲哚和犬尿酸及其衍生物，酪氨酸可被转化为对甲酚；
- ④脂质代谢中，亚油酸可被代谢为共轭亚油酸，胆固醇可转化为胆汁酸，胆碱可产生三甲胺再生成氧化三甲胺；
- ⑤地中海饮食、非洲饮食、亚洲饮食、西式饮食、生酮饮食等饮食模式对菌群和健康有不同影响。
主编推荐语
数以万亿计的细菌生活在人类的肠道中，它们代谢饮食成分以获得营养和能量，同时产生代谢物。近期，Foods期刊发表了湖南师范大学尹佳与团队关于饮食成分、微生物代谢物与人类健康的综述。本文描述了一些食物成分是如何被肠道菌群代谢的，产生的代谢产物与宿主健康和疾病的关系，并介绍了世界各地的一些饮食模式。
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Dietary Components, Microbial Metabolites and Human Health: Reading between the Lines
饮食成分、微生物代谢物与人类健康：字里行间的解读
10.3390/foods9081045
2020-09-03, Review
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Trillions of bacteria reside in the human gut and they metabolize dietary substances to obtain nutrients and energy while producing metabolites. Therefore, different dietary components could affect human health in various ways through microbial metabolism. Many such metabolites have been shown to affect human physiological activities, including short-chain fatty acids metabolized from carbohydrates; indole, kynurenic acid and para-cresol, metabolized from amino acids; conjugated linoleic acid and linoleic acid, metabolized from lipids. Here, we review the features of these metabolites and summarize the possible molecular mechanisms of their metabolisms by gut microbiota. We discuss the potential roles of these metabolites in health and diseases, and the interactions between host metabolism and the gut microbiota. We also show some of the major dietary patterns around the world and hope this review can provide insights into our eating habits and improve consumers’ health conditions.
First Authors:
Yao Guo
Correspondence Authors:
Jia Yin
All Authors:
Yao Guo,Xiaohan Bian,Jiali Liu,Ming Zhu,Linda Liu,Tingyu Yao,Congjia Tang,Vinothkannan Ravichandran,Peng Liao,Konstantinos Papadimitriou,Jia Yin
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